PEGASUS Takes Flight for Kids with Brain Injuries

Winged horse merged with a glowing brain and neural patterns against a cosmic background

When a child arrives at an ICU with severe traumatic brain injury, every minute counts and every decision matters. That’s exactly the problem the Pediatric Guideline Adherence and Outcomes (PEGASUS) program was built to solve.

Developed in 2011 at the Harborview Medical Center, a Level I Trauma Center affiliated with the University of Washington School of Medicine, PEGASUS was created to close the so-called “know-do” gap, translating Brain Trauma Foundation guidelines into bedside practice. The program trains key staff, redesigns workflows, and provides ongoing coaching.

Published in Critical Care Medicine on March 27, 2026, a new study shows the model can reach far beyond Seattle. Across 16 hospitals in Argentina, Chile, and Paraguay, children with isolated severe traumatic brain injury at PEGASUS hospitals showed 8 percentage points higher guideline adherence than those receiving standard care. This determination came from the first randomized trial of an implementation science approach to improving care in adult or pediatric traumatic brain injury.

The reach of PEGASUS is backed by federal investment: the study was supported by a grant from the U.S. National Institute of Neurological Disorders and Stroke. As Dr. Monica Vavilala of UW Medicine clarified, this approach can be adopted by hospitals around the world, whether or not they are Level I Trauma Centers.

Honoring Victims, Healing Brains: 2026 National Crime Victims’ Rights Week

National Crime Victims’ Rights Week (NCVRW) runs April 19 – 25, 2026, marking its 45th year. First proclaimed in 1981 by President Ronald Reagan, the week brings communities together to recognize the impact of crime, honor survivors, and renew commitment to victims’ rights.

Three years following its founding, in 1984, Congress passed the Victims of Crime Act to help victims navigate the tangible costs of surviving a crime, establishing the Crime Victims Fund. The law declared its purpose to assist victims “as soon as possible in order to reduce the severity of the psychological and emotional consequences of the victimization.”

That connection to brain injury is disturbing. Over 75% of domestic violence survivors suffer single or repeated traumatic brain injuries. Sometimes termed DV-TBI, most of these traumas go unreported. (Medical professionals are less likely to ask about concussions and other invisible injuries caused by domestic violence.) Assault. though, has been reported as the third most common cause of TBIs, reportedly accounting for about 10% of all cases.

The Department of Justice’s Office for Victims of Crime has declared the theme of 2026 NCVRW to be Listen. Act. Advocate. Protect victims, serve communities. As stated by the office of Chattanooga, TN Mayor Tim Kelly: “The theme emphasizes the critical need to remove barriers, meet survivors and their families where they are, and foster hope in order to build a safer, healthier community.”

Federal Government Joins States in Psychedelic Exploration

This morning, April 18, 2026, the federal government joined many states by committing to exploration of a brain injury treatment – “President Trump on Saturday signed an executive order to expedite research into the psychedelic ibogaine – a drug championed by podcaster Joe Rogan – so it can be used to treat PTSD in veterans and traumatic brain injuries,” reported the New York Post.

Heavily championed by the Secretary of Health and Human Services Robert F. Kennedy, ibogaine has recently been gaining a reputation for its treatment possibilities. Last month, March 1, 2026, the New York Times reported on one man’s treatment story. Due to federal limitations, he had to visit Mexico to be treated with  ibogaine. (In the United States, clinical studies began at Stanford University in 2022. Results have strongly suggested that ibogaine is effective in treating traumatic brain injury.)

Generation Alpha’s Trending Trauma

Speaker presenting to attentive diverse audience about online safety and 'Blackout Challenge' risks and prevention

In February 2026, nine-year-old JackLynn Blackwell died in her Stephenville, Texas backyard with a cord around her neck after seeing the “blackout challenge” online. A repackaging of the “choking game” that was first catalogued by the CDC in 2008, the blackout challenge is causing yourself to pass out. (This, in turn, causes “permanent, irreversible brain damage”.) It exploded on TikTok in 2021, as the For You algorithm began pushing self-strangulation videos to young users chasing a brief euphoric high from cerebral hypoxia. The trend has shown its lasting power: In South Orange Middle School in New Jersey, two students passed out after engaging in the challenge in 2024.

The blackout challenge has been noticed by politicians: on October 8, 2024, a bipartisan coalition of 14 attorney generals filed separate enforcement actions. “TikTok claims that their platform is safe for young people … [but] young people have died or gotten injured doing dangerous TikTok challenges,” remarked the group’s co-leader Letitia James (NY). In a March 23, 2026 press release, Congressman Jimmy Patronis (FL) stated, “As a parent, I cannot ignore the very real danger [the blackout challenge] poses to our children. Too many families have already suffered unimaginable loss.”  

Beyond concern, this childhood “thrill-seeking” has prompted some schools to take action. In New York, New Jersey and other states, schools have issued parental advisories in an attempt to protect children’s developmentally immature brains. One can hope that this trend is waning in popularity, and will soon be remembered only as an unfortunate episode in Generation Alpha’s past.

Tax Day Challenge for the Brain Injured

Tax documents, calculator, coffee mug labeled 'TAX SEASON', and April 2026 calendar showing Tax Day on the 15th.

Tax Day is stressful for nearly everyone, but the pressure can be particularly harmful for brain injury survivors. A 2024 study in Archives of Physical Medicine and Rehabilitation found that 70% of adults with acquired brain injury said their injury affected their ability to handle financial tasks, and 58% felt stressed or anxious about finances. Stress is, of course, a known trigger for neurological symptoms.

According to statistics, prior to injury, 82% of TBI survivors were employed, meaning most were taxpayers. Two years post-injury, 60.4% of moderate-to-severe TBI survivors are unemployed, according to a one study available of PubMed. Many of those who remain employed still struggle cognitively with complex tasks. Tax filing is assuredly a complex task, regardless of brain injury statis.

For brain injury survivors who cannot manage the process alone, but cannot afford professional help, the Internal Revenue Service has many free resources to provide assistance (https://www.usa.gov/help-filing-taxes). “The VITA grant program is an IRS initiative designed to support free tax preparation service for the underserved through various partner organizations.” Tax Counseling for the Elderly (TCE), “focuses on questions about pensions and retirement-related issues.” Additionally, the IRS Free File provides guided software and fillable forms, available if your adjusted gross income is $84,000 or less. For military service members, MilTax offers free tax assistance.

GLP-1 Drugs Surprising Neuroprotective Qualities

Diagram of GLP-1 (7-36) amide peptide showing amino acid sequence, side chains, chemical formulas, and α-helix structure

The weight-loss drug semaglutide, sold under the names Ozempic and Wegovy, may do far more than shrink waistlines. Research suggests it could also shield the brain after traumatic injury.

A 2026 study published in Neural Regeneration Research by scientists at Beijing Tiantan Hospital, and available in the PubMed database, found that semaglutide reduced brain swelling, preserved the blood-brain barrier, and blocked dangerous inflammatory cascades in mice with traumatic brain injuries. “Our findings reveal the dual anti-inflammatory and neuroprotective roles of semaglutide, providing important preclinical evidence for its clinical application in the acute phase of traumatic brain injury,” the researchers wrote.

The possibilities are enormous. Last year, a University of Wisconsin–Madison retrospective study of more than two million stroke patients found that those taking semaglutide had a mortality rate of just 5.26%, compared with 21.61% for non-users.

While human clinical trials for TBI are still needed, scientists say GLP-1 drugs represent the most promising new avenue for brain injury treatment in decades.

Congress Has Been Flying Blind on Veteran Brain Injury Spending for Years

Shiny golden dollar sign with stacks of bills and coins behind

The Special Disabilities Capacity Report is Congress’s primary tool for deciding how much to invest in VA’s TBI treatment infrastructure. If the numbers feeding that decision are wrong, the veterans who depend on that care pay the price.

A February 2026 review by the VA Office of Inspector General revealed that in FY 2023, the VA reported the wrong financial data for traumatic brain injury, using obligations rather than actual expenditures, thereby overstating actual TBI spending. More so, they failed to report TBI spending at both the geographic service area and national levels as required by law. The DVA Office of Inspector General’s Report 25-01863-31 also determined that VA’s capacity data did not capture community care services or the extent to which bed capacity was used at its specialized rehabilitation centers.

Pointedly, these data errors are the same as those that have been flagged in prior years. This raises questions about whether Congress receives an accurate picture of VA’s TBI treatment infrastructure. As Iowa Rep. Mariannette Miller-Meeks, Chairwoman of the House VA Health Subcommittee, stated at a March 2026 oversight hearing: “Wrong data takes resources away from [other] areas of need.”

Bounce, Track, Heal: The Surprising Science Behind Roofball and Brain Injury Recovery

Roofball is exactly what it sounds like: players throw or hit a ball onto a sloped roof, and opponents return it before it stops. Originating in America as early as the 1960s*, the sport exploded in popularity after a 2023 Reddit post showcased the Roofball World Championships, racking up 500,000+ views. In 2024, the Roofball World Championship even aired on ESPN.

The game uses simple equipment: a ball, a roof, and competitive spirit. Players score points based on ball placement, with gutters and roof angles adding unpredictable bounces that demand quick reflexes. It can be played one-on-one or with a team, usually during the warmer months of spring and summer. Now governed by the Roofball Federation of America (RFA), which has a presence in multiple states, from New Jersey to Oklahoma, it features regional tournaments. Recreationally, the sport can be played one-on-one or with teams.

Beyond fun, roofball’s rapid tracking and catching may benefit brain injury recovery. A 2025 randomized controlled trial published in Archives of Physical Medicine and Rehabilitation, and available on the PubMed database, found that ball-sport-based exercise therapy significantly improves motor function, balance, and quality of life in acquired brain injury patients. As hand-eye coordination disruption is among the most common deficits after brain injury, the repetitive coordination of handling a bouncing ball drives the neuroplasticity essential for recovery.

Roofball shows that healing can start on your own roof.

*Other reports state that it originated is Oregon in 1998.

Study Bolsters Push for Personalized Treatment

Poster with the text 'Every Brain Injury is Different' overlaid on abstract neural network graphics

A study published in the journal Neurology (epub April 3, 2026; print April 28, 2026), and currently available through the NLM PubMed database, reveals evidence that traumatic brain injuries affect each person’s brain in remarkably unique ways. While such a scientific revelation may seem evident to survivors, it challenges one-size-fits-all treatment approaches.

Researchers led by Jake Mitchell of Monash University (Australia) analyzed brain scans from 407 TBI patients and 224 healthy controls using normative modeling, a technique that measures individual brains against healthy population norms much like pediatric growth charts.  Co -authored by researchers at the VA Palo Alto Healthcare System, the study found that no more than 23% of patients shared an extreme deviation in the same brain region.

The findings help explain why nearly 30 clinical trials for acute TBI treatments have failed to identify effective therapies. The study results also bolster the case for personalized brain injury medicine. 

Mississippi Joins States for Psychedelic Experimentation

A neon-lit chemical molecular structure floating in a colorful cosmic nebula with stars and galaxies.

Mississippi is now following Texas and a handful of other states, by positioning itself on the frontier of a potential neurological revolution. On March 19, 2026, Mississippi Governor Tate Reeves made history by signing HB 314 into law, authorizing the Mississippi State Department of Health to use $5 million of Mississippi’s opioid settlement money to fund clinical trials for the drug ibogaine. The bill takes effect July 1 and allows Mississippi to coordinate trials with other states, including Texas, which has already committed to its own program.

A psychoactive substance derived from the root of a plant native to Africa, ibogaine has been used for centuries in spiritual and healing ceremonies. More recently, it has gained scientific interest for its potential to treat opioid and cocaine addiction. Research suggests it increases signaling of important brain molecules linked to drug addiction and depression. Currently a Schedule I controlled substance, Americans seeking treatment must travel abroad at costs that reportedly reach up to $50,000 per session.

As stated by Dr. Nolan Williams, who was involved in the landmark 2024 Stanford University study that brought attention to the use of ibogaine for brain injury, “no other drug has ever been able to alleviate the functional and neuropsychiatric symptoms of traumatic brain injury.”